Tumor necrosis factor-a inhibition and palmoplantar pustulosis: Janus-faced therapy?
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چکیده
منابع مشابه
Amicrobial pustulosis of the folds and palmoplantar pustulosis simultaneously induced by different tumor necrosis factor-α inhibitors: Demonstration of a shared pathophysiology
APF: amicrobial pustulosis of the folds IBD: inflammatory bowel disease IFN-a: interferon-a PPP: palmoplantar pustulosis TNF-a: tumor necrosis factor-a INTRODUCTION Amicrobial pustulosis of the folds (APF) and palmoplantar pustulosis (PPP) are 2 rare autoinflammatory neutrophilic dermatoses. Many studies report PPP triggered by treatment of inflammatory bowel disease (IBD) with tumor necrosis f...
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Despite, the fact that palmoplantar pustulosis is still widely known by this name, it is currently regarded as a disease distinct from psoriasis. The real cause is still unknown. Septic foci have been blamed, but their removal may not cure eruptions. A case series of de novo occurrence of palmoplantar pustulosis induced by tumor necrosis factor–alpha antagonist therapy has been reported. It has...
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INTRODUCTION Palmoplantar psoriasis (PP) and palmoplantar pustulosis (PPP) are diseases affecting the hands and/or feet that can cause marked physical discomfort and functional disability. The tumor necrosis factor-alpha antagonists adalimumab, etanercept, and infliximab, the interleukin (IL)-17A inhibitors ixekizumab and secukinumab, and the IL-23 or IL-12/IL-23 inhibitors guselkumab and ustek...
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A multicentre case-control study of 216 patients with palmoplantar pustulosis and 626 controls with miscellaneous dermatoses showed a considerably higher prevalence of smoking in the group with palmoplantar pustulosis. This was the first indication that smoking may be an important factor in this skin disease, possibly by affecting the inflammatory responses of the skin.
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Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disorder characterized by osteoarticular and dermatological manifestations. The denotation was first proposed by Chamot et al. in 1987 after investigation of 85 cases (Chamot et al., 1987). The most common site of SAPHO syndrome is the upper anterior chest wall, characterized by predominantly osteosclerotic lesions and h...
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ورودعنوان ژورنال:
- The Journal of rheumatology
دوره 34 2 شماره
صفحات -
تاریخ انتشار 2007